Crystagen

Crystagen

$120.00

CRYS

What is CRYS/h3>
Crystagen (20 mg) is supplied strictly for laboratory research and analytical applications, commonly referenced in endocrine axis, organ-signaling, and regulatory pathway studies.

Specifications:
  • Strength: 20 mg per vial
  • Format: Lyophilized powder
  • Category: Cellular & Regulatory Signaling
  • Documentation: COA available

Research Use Only — Not for Human Consumption.

SKU: VE-CRYS-020 Category:

Description

  • About Crystagen

    Crystagen — a synthetic Glu-Asp-Pro tripeptide (EDP, MW 359.34 g/mol, C₁₄H₂₁N₃O₈) from the Khavinson peptide bioregulator series — is a thymus-derived synthetic short peptide studied as a model immune-system cytoprotective signal in immunology and aging research. It is supplied as a laboratory-grade lyophilized powder intended strictly for analytical and non-clinical research applications.

    As a member of the AC-6 peptide complex from the St. Petersburg Institute of Bioregulation and Gerontology, Crystagen is investigated for its selectivity toward thymic epithelial cell and splenic lymphocyte signaling models. Preclinical work has examined B-cell activation, thymocyte proliferation (PCNA expression), and immunomodulatory gene expression pathways. Researchers use Crystagen in primary thymocyte, Jurkat T-cell, and Ramos B-cell models to study immune checkpoint signaling, cytokine pathway modulation (NF-κB, IL-6), and cellular stress response under standardized in vitro conditions.

    COMMON RESEARCH APPLICATIONS

    B-Lymphocyte Activation & Immune Modulation
    Crystagen is examined in Ramos B-cell and primary splenocyte models under mitogenic challenge to study B-cell surface marker expression (CD19, CD20, CD69), immunoglobulin secretion pathway markers, and proliferation endpoint characterization.

    Thymocyte Proliferation & Thymic Cytoprotection Assays
    Used in primary thymocyte and thymic epithelial cell (TEC) models to assess PCNA expression, Ki-67 proliferation index, and thymic cortex/medulla compartment marker integrity under oxidative or aging-model stress conditions.

    NF-κB Pathway Modulation in Immune Cells
    Examined in Jurkat T-cell and RAW 264.7 macrophage models under cytokine challenge (TNF-α, IL-1β) to characterize effects on NF-κB p65 nuclear translocation, IL-6 and IL-8 secretion, and inflammatory pathway endpoint modulation.

    Comparative Khavinson Immune Peptide Screening
    Benchmarked alongside related thymic bioregulators (Thymalin, Vilon) to characterize tissue-selective immune signaling profiles, B- vs. T-cell activity ratios, and shared vs. distinct pathway features within the short peptide bioregulator class.

  • Chemical Identity

    Compound Name: Crystagen

    Internal Catalog Code: Crystagen

    CAS Number: Not registered (synthetic tripeptide EDP; Glu-Asp-Pro)

    Molecular Formula: C₁₄H₂₁N₃O₈

    Molecular Weight: 359.34 g/mol

    Physical Properties

    Appearance: Lyophilized powder

    Quality & Testing

    Purity: As listed on lot-specific COA

    Testing Method : HPLC (as applicable) · identity confirmation per COA

    Verification

    COA: Lot-specific, included with order (QR on label)

    Handling & Storage

    Storage Temperature: Store desiccated at −20°C for long-term; 2–8°C short-term. Protect from light. Refer to SDS/COA for compound-specific handling.

    Light Sensitivity: Protect from light

    Moisture: Store desiccated when applicable

    Available Strengths: 20 mg

    SKU (20 mg): VE-CRYS-020

    • What is this product?
      Crystagen (EDP, Glu-Asp-Pro) is supplied as a lyophilized synthetic tripeptide (MW 359.34 g/mol, C₁₄H₂₁N₃O₈) from the Khavinson bioregulator series for laboratory research use only. It is studied as a model thymic immune cytoprotective peptide. Available as VE-CRYS-020 (20 mg).
    • What purity and testing methods are used?
      Each lot is tested by reverse-phase HPLC and MS confirmation to ≥98% purity with sequence verification (Glu-Asp-Pro confirmed). A lot-specific COA is included with every order, accessible via QR code on the label.
    • What are the key chemical identifiers?
      No registered CAS number (synthetic tripeptide complex) · Molecular formula C₁₄H₂₁N₃O₈ · MW 359.34 g/mol · Sequence: H-Glu-Asp-Pro-OH · Synonyms: EDP, AC-6 peptide complex, Khavinson thymic tripeptide.
    • How is Crystagen reconstituted for research use?
      Dissolve in sterile water or PBS (pH 7.0) at ~5 mg/mL. Use immediately or aliquot and store at −80°C. Avoid repeated freeze-thaw cycles. Protect from light and moisture.
    • What is the recommended storage upon receipt?
      Store immediately at −20°C in a desiccated environment. Short-term at 2–8°C acceptable for up to 2 weeks of active use. Inspect vials for integrity upon receipt.
    • What is a COA and why does it matter?
      A COA documents lot-specific purity (HPLC ≥98%), sequence verification (MS: Glu-Asp-Pro confirmed), and appearance. Each Crystagen lot ships with a QR-accessible COA. Review before use to confirm identity and purity meet your experimental requirements.

Additional information

Dosage

20mg

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